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While both agents struggled with the inherent GI burden typical of GLP-1RAs, efpeglenatides limitations were largely dose-related and within manageable expectations, whereas taspoglutides combination of severe immunogenicity and hypersensitivity reactions rendered it clinically unviable

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Given the global trend of population aging, the number of individuals living with AD is expected to increase remarkedly, necessitating a shift in the care provided to these individuals and the resources re-allocated [6]

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