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In the Redox Biology study described earlier [5], individuals with type 2 diabetes treated with GLP-1 receptor agonists demonstrated reduced ROS production, restoration of mitochondrial membrane potential, improved oxygen consumption, and lower levels of myeloperoxidase (MPO)
The human IGF-1 literature primarily involves mecasermin (native recombinant IGF-1, brand Increlex), approved for growth failure in children with severe IGF-1 deficiency
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