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Our findings provide the new evidence that GSTP inhibited HMGB1 release via binding to HMGB1 in the nucleus independent of its transferase activity
By contrast, evidence in neurodegeneration and inter-organ propagation remains preliminary
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Gastaldelli A, Cusi K, Fernndez Land L, Bray R, Brouwers B, Rodrguez (2022) Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial
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