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In diet-induced obese (DIO) mouse models, 5-Amino-1MQ treatment produced significant reductions in body weight, white adipose tissue mass, and adipocyte cell size without significant effects on food intake suggesting a metabolic rather than appetite-suppressing mechanism

J Cell Biol 217:19151928 Watanabe F, Hashizume E, Chan GP, Kamimura A (2014) Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women

Elevated homocysteine levels can inhibit the activity of MS enzyme, leading to decreased SAMe production

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