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As with any wellness change, results vary from person to person

However, because tesofensine has an extraordinarily long half-life (200+ hours), this initial peak is less clinically significant than the cumulative buildup that occurs over the first 1014 days of daily dosing once steady state is reached, plasma levels remain relatively constant throughout the 24-hour dosing interval

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If you've had a severe reaction in the past, your provider may take steps to reduce the risk of a repeat reactionsuch as monitoring you after a vaccine or prescribing a different formulation