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In addition to the direct impact on the proportion of gut bacteria, GLP-1RAs were found to upregulate tight junction proteins in the intestinal mucosa, which helps prevent the translocation of bacteria to the blood
Typically, only one Phase 2 proposal is awarded per Phase 1 award
Adults aged 25-34 appear particularly open to oral GLP-1s, potentially making them the generation that accelerates the mainstream adoption of weight loss pills in the UK
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