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Furthermore, the EMA has withdrawn the weight loss medication rimonabant, a selective cannabinoid type 1 receptor antagonist, due to its reported links to increased risks of depression and suicide [70]

Beyond glycemia, insulin exerts clinically leveraged effects on potassium homeostasis (enabling management of hyperkalemia) and triglyceride metabolism (via upregulation of lipoprotein lipase, offering a powerful intervention in severe hypertriglyceridemia and hypertriglyceridemia-induced pancreatitis)

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Pretreatment with intravenous CoQ10 (5 mg/kg) reduced serum ALT and markers of oxidative stress, but had no effect on liver glutathione levels (Amimoto 1995)