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GLP-1 agonists work by mimicking the action of the naturally occurring GLP-1 hormone, which stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite
Children with ASD commonly exhibit increased intestinal permeabilityoften referred to as leaky gutwhich allows microbial metabolites, such as short-chain fatty acids (SCFAs) and neuroactive compounds (e.g., 5-HT, GABA), to enter systemic circulation (Ullah et al., 2024)
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