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Related Stories Researchers trace soaring poison control calls to semaglutide approval for weight loss Oral semaglutide reduces heavy drinking in adults with alcohol use disorder Study links semaglutide and tirzepatide to fewer anxiety and depression diagnoses in obesity care For every patient population, a specified trial was conducted to compare semaglutide with other drugs used to treat T2DM including sodium-glucose cotransporter-2 inhibitors (SGLT2i), insulins, metformin, sulfonylureas (SUs), thiazolidinediones (TZDs), dipeptidyl-peptidase-4 inhibitors (DPP-4i) and other GLP-1Ras

Tirzepatide (as Mounjaro or Zepbound) is approved for type 2 diabetes and/or weight management in the following countries: Additionally, in December 2024, the United States FDA revised the indication for tirzepatide (branded as Zepbound) to include the treatment of moderate to severe obstructive sleep apnea

The results for the treatment policy estimand are also presented in Table 2 and ESM Table 2 and are broadly similar to the results for the trial product estimand

Abruptly stopping can affect blood sugar levels and weight management progress