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Antidiabetic Drugs As opposed to behavioral modification, pharmacologic therapy with antidiabetics achieves a uniform reduction in the IGT and IFG conversion to T2DM

While this is generally health-promoting, individuals with naturally low blood pressure should start with lower doses and ensure they are well-hydrated to avoid dizziness

Animals were maintained individually in standard, species-appropriate housing and managed consistently during the study, including providing access to activity/exercise

Mild oxidative agents such as the reactive nitrogen species (RNS) are therefore potentially more relevant from a mechanistic point of view in vivo, as they modify thiols in a more controlled and often reversible manner