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Always obtain semaglutide from a licensed pharmacy with a valid prescription
Trial FLOW (Perkovic et al., NEJM 2024) Design Phase 3 / event-driven Population 3,533 adults with T2D and CKD Key result 24% reduction in kidney disease progression and CV death (HR 0.76
This depends on how NICE assesses retatrutides cost-effectiveness against Mounjaro
Recognised side effects that require medical attention include severe abdominal pain (which could indicate pancreatitis), persistent nausea and vomiting leading to dehydration, signs of gallbladder problems such as jaundice or right upper abdominal pain, changes in vision (especially if you have type 2 diabetes with pre-existing diabetic retinopathy), or symptoms of hypoglycaemia if you are taking other diabetes medications
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