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This means its effects are intriguing but still require more scientific validation before being fully accepted in medical practice
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Starting at the lower end of dosing ranges and adjusting upward based on response prevents overshooting
The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure
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