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Aplastic anemia is thought to be either acquired or inherited, though the exact cause is not known
Cellular senescence is characterized by a stable arrest in the cell cycle and encompasses a range of cellular changes that culminate in the development of a complex, pro-inflammatory secretory profile known as the senescence-associated secretory phenotype (SASP), which plays a critical role in fibrosis and tumors by affecting numerous processes, including invasion and therapy resistance 10
Free radicals can also be caused by inflammation
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