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HELLP is a type of thrombotic microangiopathy (TMA) It is the most common cause of a TMA in the late second/third trimesters It is important to distinguish between HELLP and thrombotic thrombocytopenia purpura (TTP) and hemolytic uremic syndrome (HUS) as their treatment differs greatly with urgent delivery indicated only for the former
Milella M, Ricciardi MR, Bergamo P, Scerpa MC, Gervasoni J, Petrucci MT, Chiaretti S, Tavolaro S, Ciuffreda L, Decandia S, Libotte F, Abrams SL, Steelman LS, Konopleva M, Cognetti C, Foa R, Andreeff M , McCubrey J, Tafuri A
At 60 h-post injection, the mice were sacrificed and the biodistribution determined upon fluorescence imaging of the respective organs