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Cohorts were divided into healthy individuals without cirrhosis and participants with cirrhosis classified according to Child-Pugh class A, B, or C

More studies are needed to clarify the underlying mechanism of drug and GLP-1 actions on reward circuits

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For example, the benefits for overweight/obese individuals were highlighted in the SURMOUNT-1 trial, which involved overweight/obese individuals with an average weight of 104.8 kg and a BMI of 38.0, indicating that tirzepatide could be a new option for weight loss in this specific population