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No significant negative interactions are known, but optimal absorption is achieved when taken at different times
My feeling is that if you use any smaller gauge of needle you risk damaging the surrounding tissue at the injection site
An apparent paradox is that whereas GLP-1 increases glucose-stimulated insulin secretion in the isolated pancreas fulfilling the definition of an incretin but it lowers insulin secretion in physiologically relevant conditions [6, 10, 18]
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