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This route enables gut-derived signals to rapidly influence microglial activation and neuroinflammation in areas like the substantia nigra (Table 2)

Homocysteine accumulates in the blood, causing vascular damage and micro-clotting, while downstream glutathione synthesis grinds to a halt

DIM is a compound found in broccoli, cauliflower, and other cruciferous vegetables that may be able to balance hormones, particularly through an improvement in estrogen metabolism.41 We discuss DIM and its alternatives for alleviating menopause symptoms at length in our guide to the best menopause supplements

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