Without enough B12, the adrenal glands, which produce stress hormones like cortisol and adrenaline, can become fatigued
Pre-clinical research conducted primarily in animal models informs the hypotheses for its use, but no large randomized controlled trials in humans have confirmed efficacy for any outcome - including gut-lining support, tissue-related processes, or any other claimed mechanism
The protein requirements on semaglutide are non-negotiable if you care about body composition
Mansouri HR, Gracia Carmona O, Jodlbauer J, Schweiger L, Fink MJ, Breslmayr E, Laurent C, Feroz SP, Goncalves LC, Rial DV, Mihovilovic MD, Bommarius AS, Ludwig R, Oostenbrink C, Rudroff F (2022) Mutations increasing cofactor affinity, improve stability and activity of a BaeyerVilliger monooxygenase