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475 NK cell autophagy defects cause impaired mitochondrial polarization, but autophagy activation can restore functionality, 476 suggesting spatiotemporally specific autophagy regulation
Another study conducted by Shen et al
Molecules 27:5252 Raza A, Galili N, Smith SE, Godwin J, Boccia RV, Myint H, Mahadevan D, Mulford D, Rarick M, Brown GL (2012) A phase 2 randomized multicenter study of 2 extended dosing schedules of oral ezatiostat in low to intermediate-1 risk myelodysplastic syndrome
p53 controls both apoptosis and senescence by promoting p21 transcription, resulting in cell cycle arrest during DNA repair
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