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Vaghani V, Chandwani S, Hirschmann M, Dibaj S, Lacerda L, Roarty E, Zhang J, Rinsurongkawong W, Lewis J, Lee JJ, Roth JA, Swisher SG , Heymach J, Ta B, Simon GR
It is strongly associated with both frontotemporal dementia (FTD), either alone or as part of ALS-FTD
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It is being actively investigated in scientific research for its role in energy balance regulation, neuroendocrine signaling pathways, and metabolic disease models particularly obesity and type 2 diabetes
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