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Transdermal delivery systems may additionally cause local skin reactions , including redness, itching, or irritation at the application site

Moreover, because GLP-1R is expressed throughout the body, stimulation with a GLP-1R agonist or indirectly with a DPP-IV inhibitor can have a broad systemic effect on systemic metabolism, which, in turn, ameliorates peripheral and central insulin resistance in AD and MD (Athauda and Foltynie, 2016)

Industry analysts increasingly believe delivery innovation could become just as important as efficacy itself