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Also, evidenced are frameshift mutations observed due to genetic alterations of MMR proteins, leading to the generation of neoantigens [109]
D.et al (2003)
MiR-200a is involved in regulating redox imbalance, and the suppression of aortic endothelial miR-200a expression under hyperglycaemic conditions increases the expression of kelch-like ECH-associated protein 1 (Keap1), which is linked to Nrf2 binding and leads to the inactivation of Nrf2 antioxidant signalling, thereby inducing diabetic vascular endothelial dysfunction [91]
Au niveau du foie, il limite laccumulation de toxines
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