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Who should use cautionor avoid tirzepatide Tell your clinician if you have or have had: Personal or family history of medullary thyroid carcinoma (MTC) or MEN2 Pancreatitis , significant gallbladder disease , or severe GI disorders (e.g., gastroparesis) Pregnancy or breastfeeding (not recommended)

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Patients should report any suspected side effects via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app)