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Moreover, since the inception of this study, multiple metabolic mechanisms promoting drug resistance have been suggested for 5FU treatment, including changes in amino acid metabolism 69,70 , serine and glycine metabolism 71,72,73 and glycolysis 74,75 , corroborated within our study and independently validating our findings

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The true monthly cost is $249, but the advertised price of $179 is one of the most aggressive intro discounts in the lineup, which sets up sticker shock at month two

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