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Atractylodes macrocephala exhibits anti-hyperuricemic and anti-inflammatory properties in animal models, reducing IL-1 and TNF- levels while activating AMPK/SIRT1 signaling and suppressing NF-B-mediated macrophage polarization toward pro-inflammatory phenotypes (Qian et al., 2023)
Clinical trial durations provide guidance as well
Norwegian J Zool 20:209-212 Ben-Smith A, Lammas DA, Behnke JM (2002) Effect of oxygen radicals and differential expression of catalase and superoxide dismutase in adult Heligmosomoides polygyrus during primary infections in mice with differing response phenotypes
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