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The anti-diabetic drug exenatide, a glucagon-like peptide-1 receptor agonist, counteracts hepatocarcinogenesis through cAMP-PKA-EGFR-STAT3 axis
Other risks include pancreatitis, gallbladder disease, and kidney injuries
The findings suggest that weight loss can enhance the effectiveness of circulating estradiol (a potent form of oestrogen), as lower body fat reduces estrone production, which can counteract the beneficial effects of estradiol
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