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This difference is likely to be related to the more tightly packed ECD interface of RAMP2 and CTR, driven by the interactions with P37 Cagri , and the preferential CTR engagement by Cagri via a bypass conformation, as discussed below in the context of CTR complexes
The differential metabolites were screened by using variable importance in projection (VIP) score of the OPLS model combined t -test
van Can J, Sloth B, Jensen CB, Flint A, Blaak EE, Saris WH
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