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10.1371/journal.pbio.3000201 46 FuS.WangY.ZhouJ.LiuY.WanJ.XuL.et al (2025)
By disrupting FOXO4-p53 interactions, it promotes apoptosis in senescent cells, reducing inflammation and improving cellular health (3)
Targeting IGF-1R in cancer The vast expression of IGF-1R in neoplastic cells and tissues combined with its crucial roles in cancer cell growth is making this tyrosine receptor an attractive target to combat malignant diseases
Re-balance Gut Motility As the smooth muscle of the gut lining becomes destroyed, some colon segments get out of sync. As the gut heals, its not always going to heal evenly
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