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In the System Xc/GSH/GPX4 axis, Nrf2 positively regulates SLC7A11 (xCT, a subunit of System Xc), promoting cystine import and glutamate export, thereby increasing intracellular cystine levels and facilitating GSH synthesis (Lewerenz et al., 2013)
Omega-3s are powerful, but they work best alongside other strategies like stress management, regular exercise, and adequate sleep
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Mast Cell Activation Syndrome. Cleveland Clinic, Accessed 14 May 2026
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