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A class of peptic ulcer and antacid drugs called histamine H2 receptor agonists, including Tagamet, Zantac, and Pepcid Anticonvulsants including phenobarbital, primidone, and phenytoin Bile acid sequestrants including colestipol and cholestyramine, which lower cholesterol Chemotherapy medications like methotrexate Metformin, which is a diabetes drug Proton pump inhibitor drugs used to treat acid reflux, such as omeprazole (Prilosec), esomeprazole (Nexium), or lansoprazole (Prevacid) Tetracycline, an antibiotic Lastly, it is also essential that you communicate with your provider if you have kidney disease or an allergy to cobalt or any other medication, vitamin, dye, food, or preservative

1 Education for awareness and health care and control of hyperglycemia, dyslipidemia and hypertension are key strategies for slowing the onset and worsening of DR, similar to other MDS-related complications

Multilayered approaches that integrate distinct metabolic components and ML have the potential to determine the systemic consequences of whole subsets of metabolites and nontargeted axes of variation, providing further insight into disease development and progression [22]

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