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Acting on both pathways may help enhance metabolic control and lead to more weight loss than GLP1only medications like Wegovy

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Furthermore, ROS interacts with cellular transduction pathways like protein kinase C/extracellular signal-regulated kinases (ERK)/mitogen-activated protein kinase (MAPK) pathway that can affect cell growth, cell proliferation, differentiation, apoptosis and gene expression [10, 11]

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PNAS Nexus 4 , pgaf042 (2025)

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A deficiency can lead to megaloblastic anemia, causing fatigue and weakness

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