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Its antioxidant effects involve modulation of superoxide dismutase and catalase enzyme activity, reducing the oxidative stress burden in aging tissues
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Cardiovascular outcomes, long-term efficacy and safety In people with T2D and established cardiovascular disease, the international guidelines for T2D recommend the use of GLP-1 RA or sodium glucose co-transporters 2 inhibitors (SGLT-2i) as first-line treatment (independent of HbA1c), based on multiple trials demonstrating their cardio-renal benefits [109]
27: A week after the FDA denied Venatorx Pharmaceuticals and Melinta Therapeutics New Drug Application for urinary tract infection (UTI) antibiotic cefepime-taniborbactam, competitor Allecra Therapeutics won approval of Exblifep in the same indication
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