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Ferreira SC, Bruns RE, Ferreira HS, Matos GD, David JM, Brandao GC, da Silva EP, Portugal LA, Dos Reis PS, Souza AS, Dos Santos WN (2007) Box-Behnken design: an alternative for the optimization of analytical methods
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The appeal of these agents stems from their capacity to modulate key pathophysiological contributors in atherosclerosis and heart failure, including oxidative stress, chronic vascular inflammation, endothelial dysfunction, dyslipidemia, and mitochondrial energy deficits ( However, the field is marked by heterogeneous and sometimes contradictory evidence
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