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When glycemic targets are not achieved, second-line treatment with insulin or third-line treatment with oral antidiabetic agents such as glyburide or metformin is required to restore maternal glycemia [236, 240,241,242,243]
In addition, zinc can lower cortisol levels
Dpp4 hep/ mice showed no change compared to Dpp4 GFP in an arginine tolerance test, indicating that islet responsivity to acute depolarization was normal (Supplemental Figure 2D)
This approach is considered an off-label (i.e
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