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This months Patent Gazette features Dunads covalent PIKfyve inhibitors, Storm Therapeutics DHX9 inhibitors, and Monte Rosas CCNE1 molecular glue degraders for biomarker-defined cancers
Nanoparticles act as protective vehicles for peptides, facilitating controlled release and improved pharmacokinetics. Fonte et al., Trends in Biotechnology Types of Novel Delivery Technologies for Peptides Lipid-based nanoparticles (LNPs) Already used in mRNA vaccines
Additionally, cancer survivors have historically been underrepresented in clinical trials, meaning specific data for this population remains limited
Ellagic acid (EA) also increased the GSH antioxidant system and diminished oxidative stress in several models of myocardial injury, such as diabetes and cisplatin-mediated heart injuries [164, 171]
