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Glucagon-like peptide-1 receptor agonist treatment does not reduce abuse-related effects of opioid drugs
in the Journal of Pharmacology and Experimental Therapeutics (which established Dihexas HGF/c-Met mechanism via Morris water maze rescue with HGF antagonist blockade) was the subject of an Expression of Concern in 2021 and was formally retracted in April 2025 by the publishing journal following investigation into image manipulation
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Treatment typically involves hydroxocobalamin injections for significant deficiency or neurological symptoms, with lifelong maintenance therapy required for pernicious anaemia
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