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It is a theoretical concern based on mechanism, not an observed outcome
Severe symptoms: emergency care Seek emergency medical care immediately for any of these: Severe, unrelenting right upper abdominal pain lasting more than 4-6 hours Fever above 100.4 degrees F with abdominal pain Jaundice (yellowing of skin or eyes) Clay-colored stools with dark urine Severe vomiting with inability to keep fluids down Pain so intense you cannot find a comfortable position These symptoms may indicate acute cholecystitis, choledocholithiasis (stone in the common bile duct), or cholangitis (bile duct infection)
doi: 10.1016/j.physbeh.2019.03.026 33 BucciarelliLCiminoVDellOssoBFiorinaP
Zepbound (tirzepatide) injection, for subcutaneous use: Full prescribing information
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