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Risperidone-induced weight gain is mediated through shifts in the gut microbiome and suppression of energy expenditure

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The processed nSREBP2 enters the nucleus and binds to sterol regulatory element sequences in target gene promoters, including HMGCR, upregulating their transcription (26)

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6.5 Metabolic disorder Metabolic dysregulation is a key mechanism in both hypertension and lung cancer, particularly involving energy metabolism, lipid metabolism, and glucose metabolism [253,254,255,256,257,258]

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