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Furthermore, the downregulation of major histocompatibility complex class I (MHC-I) molecules impairs antigen presentation, effectively hiding tumor cells from cytotoxic T lymphocytes

In 2021, Kishimoto et al., in a double-blind, placebo-controlled clinical trial, evaluated the anti-inflammatory effects of curcuRouge for 4 weeks on systemic inflammation in adults over 60 years of age in Japan [62]

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