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Based on this hypothesis and our previous work 10 , we tested in this study the combinatory killing effects of BSO, a potent specific inhibitor of GCL in glutathione biosynthesis 27 , and DPI, a widely used NOX inhibitor 28 , on HRAS G12V -transformed ovarian epithelial cells, mutant KRAS- bearing pancreatic and colon cancer cells, and murine pancreatic cancer cells harboring both KRAS and p53 mutations
B12 deficiency has been linked to depression, memory loss, and cognitive decline
Nakamoto, Y
According to the 2023 American Gastroenterological Association (AGA) guidelines, soluble fiber supplements and osmotic laxatives like polyethylene glycol (PEG) are recommended as first-line treatments for chronic constipation
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