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So I end up taking breaks throughout the year and come back to it when I feel like leaning out about 5-10 pounds
Longer use may blunt responsiveness due to IGF-1 receptor downregulation
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In a Phase 3 obesity trial, patients on the highest dose of the weekly injectable, called survodutide, lost 13% of their weight after 76 weeks, compared with 5% in the placebo group, according to data presented Sunday at the annual meeting of the American Diabetes Association and published in the New England Journal of Medicine
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