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If cancer is very sensitive to the damaging effects of free radicals, then it might be possible to develop drugs that target cancer cells specifically and prevent them from producing antioxidants or that ramp up free radical levels inside of the malignant cells, exploiting their newly discovered weakness.

A prospective, multicenter randomized controlled trial that looked at the effectiveness of 0.2% HA cream on the skin compared to a neutral cream in the treatment of people with chronic leg ulcers reported the following treatment-related side effects: Skin and subcutaneous tissue disorders : In the HA cream group, 21.2% reported skin and subcutaneous tissue disorders compared to 16.9% in the neutral cream group

Note that hemolyzed blood may interfere with results