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No sex-dependent differences were found (ANOVA (sex) F (1,30) = 0.0241, p=0.8777, Supplemental Figure 1C,D) and were again combined for all analyses
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Although isoform X1 is absent in certain higher organisms, such as mice, elephants, dogs and chickens, it is highly conserved across many other species ( via the inhibition of NOTCH1 signaling