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The GLP-1 medications for diabetes include: Dulaglutide (Trulicity) Exenatide (Bydureon, Byetta) Liraglutide (Victoza) Lixisenatide (Adlyxin) Semaglutide (Ozempic, Rybelsus) Tirzepatide (Mounjaro) People taking GLP-1s for diabetes had significant weight loss and improvements in cardiovascular factors

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To investigate the physiological functions of endogenous GLP-1 mediated via vagal sensory neurons, a rat model with vagal sensory neuron-specific GLP-1R knockdown was generated by microinjecting a viral vector expressing GLP-1R shRNA into the nodose ganglion [51]