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NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction
Current clinical guidance treats obesity as a chronic condition that may need long-term treatment for some people
Considering the effects of TNF on L cells and data from animal models, indicating that impaired glucose tolerance following high-fat diet-induced obesity can be ameliorated by anti-TNF therapy (95), one might expect a significant impact of anti-TNF treatment on glucose metabolism
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