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doi: 10.1007/978-981-13-2835-0_15 4 BlountBCMackMMWehrCMMacGregorJTHiattRAWangGet al

Simultaneously, Shc recruitment activates the Ras-Raf-MEK-ERK cascade, which drives cell proliferation through cyclin D1 transcription

In addition, we will discuss the possibility to target enzymes involved in the epigenetic machinery to modify the expression of the SST-system, thereby possibly improving therapeutic options