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There's also a hunger-hormone angle: ghrelin, the "hunger hormone" produced by the stomach when it's empty, is decreased by GLP-1 receptor agonists, which contributes to their appetite-suppressing effects
The absence of clinical evidence means that any claims regarding efficacy would be speculative and not supported by scientific data
In any case, one cannot buy PT-141 over the counter
Think of it this way: the FDA's approval is like a seal of certification for a specific purpose
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