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And with weight loss, consistency is often what turns a promising start into real progress

Semaglutide is administered as a once-weekly subcutaneous injection (marketed as Ozempic for diabetes and Wegovy for weight management) or as a daily oral tablet (Rybelsus)

In general, GLP-1 RAs help to keep blood sugar under control and also promote weight loss

The mechanistic explanation is not speculative: the glucagon receptor adds hepatic fatty-acid oxidation, adipose lipolysis and thermogenic energy expenditure that dual agonism cannot engage by design 27, and the Phase 2a MASLD readouts 8590% liver-fat reduction is a direct signature of that pathway 3