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Although numerous topical and systemic therapeutic agents and also non-pharmacologic procedural treatments have been considered in melasma management, however, the commonly available therapeutic options have several limitations including the lack of sufficient clinical effectiveness, risk of relapse, and high rate of unwanted adverse drug reactions

Cons: cash-pay only, so not ideal if you want to bill insurance

DNA kit included

The table below summarizes the percentage reduction in total fat mass from baseline at week 36: The 8mg dose produced the highest fat mass reduction at 26.1%, which represents an exceptional result in obesity pharmacotherapy