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Once complexed with Cu(II), the peptide backbone rearranges into a specific square-planar coordination around the copper ion, with donor atoms from the glycine amino terminus, the deprotonated amide nitrogen, the histidine imidazole, and a fourth position (carboxylate or water depending on pH)

Folate deficiency in these patients is usually more severe than vitamin B12 deficiency

Experts believe tablet versions could prove transformative because they are easier to take and store, and may ultimately be cheaper

ICHRA (Individual Coverage Health Reimbursement Arrangement) lets you provide tax-free health insurance benefits, while letting your employees select their own plans